Fibrinogen beta Chain anticorps (AA 150-491)

N° du produit ABIN7114194

Cet anticorps anti-Fibrinogen beta Chain est un anticorps Souris Monoclonal détectant Fibrinogen beta Chain dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Fibrinogen beta Chain anticorps (AA 150-491) (ABIN7114194)

Antigène: Fibrinogen beta Chain (FGB)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Fibrinogen beta Chain est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 6F4

Détail du produit anti-Fibrinogen beta Chain anticorps

Épitope: AA 150-491

Fonction: FGB antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 150-491aa

Immunogen: fibrinogen beta chain

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Fibrinogen beta Chain

Antigène: Fibrinogen beta Chain (FGB)

Autre désignation: FGB

Sujet:

Synonyms: Fibrinogen beta chain|Fibrinopeptide B|Fibrinogen beta chain|FGB

Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Poids moléculaire: 50 kDa

ID gène: 2244

UniProt: P02675